You could simply uninstall the programs you don't want...or you could do a complete system reformat with a windows CD(or restore disc if you have One),or boot lnto recovery mode(if your hard drive contains a recovery partition)To tell if you have a recovery partition boot up the computer,go to "MY COMPUTER" and check if two hard drives showup(one would be(C:)The other is usually(D:).
It's easier to simply uninstall any program you don't want anymore,download and run CCleaner to remove the left Over registry files(and there WILL be left over registry files),then defrag the hard drive to remove any fragmented files.
All of this will make the computer run better as well.As far as programs you NEED on your computer....we can't tell you,because we don't know what programs you have.